Nighttime Driver Behavior Prediction Using Taillight Signal Recognition via CNN-SVM Classifier

This paper aims to enhance the ability to predict nighttime driving behavior by identifying taillights of both human-driven and autonomous vehicles. The proposed model incorporates a customized detector designed to accurately detect front-vehicle taillights on the road. At the beginning of the detector, a learnable pre-processing block is implemented, which extracts deep features from input images and calculates the data rarity for each feature. In the next step, drawing inspiration from soft attention, a weighted binary mask is designed that guides the model to focus more on predetermined regions. This research utilizes Convolutional Neural Networks (CNNs) to extract distinguishing characteristics from these areas, then reduces dimensions using Principal Component Analysis (PCA). Finally, the Support Vector Machine (SVM) is used to predict the behavior of the vehicles. To train and evaluate the model, a large-scale dataset is collected from two types of dash-cams and Insta360 cameras from the rear view of Ford Motor Company vehicles. This dataset includes over 12k frames captured during both daytime and nighttime hours. To address the limited nighttime data, a unique pixel-wise image processing technique is implemented to convert daytime images into realistic night images. The findings from the experiments demonstrate that the proposed methodology can accurately categorize vehicle behavior with 92.14% accuracy, 97.38% specificity, 92.09% sensitivity, 92.10% F1-measure, and 0.895 Cohen's Kappa Statistic. Further details are available at https://github.com/DeepCar/Taillight_Recognition.Comment: 12 pages, 10 figure

The role of metalloproteinase and hypoxia conditions in endometrial cells and embryo implantation

In the process of implantation, metalloproteinase enzymes play a key role in basement membrane degradation and endometrial extracellular matrix. The activity of these enzymes is impeded by binding Tissue Inhibitors of Metalloproteinase (TIMP). The oxygen concentration in the mammalian uterus at the time of implantation is about 2-5%. It is seen that the imposition of hypoxia on cancer cells increases the expression of metalloproteinase enzymes and reduces the expression of metalloproteinase inhibitors, resulting in increased cell invasion. To know the effect of Hypoxia-Inducible Factor (HIF) and other related factors, we decided to evaluate hypoxic conditions on endometrial epithelial cells of the uterus and roll of matrix metalloproteinases (MMPs) on angiogenesis and invasion of the embryo during implantation. In this study, human and mouse endometrial epithelial cells were incubated for 24-48 hours in hypoxic conditions. Subsequently, the expression level of TIMP-1 was measured in mouse and human epithelial cells by Real-Time PCR technique. The cell viability in hypoxic conditions was evaluated by MTT assay. Our results demonstrated that hypoxia reduced the quantitative gene expression of TIMP-1 in the human and mouse endometrial epithelial cells compared to the control group. It can be concluded that applying hypoxic conditions by reducing the TIMP-1 expression and consequently increasing MMP expression, may improve the embryo implantation rate

EVALUATION OF MOBILE DEVICE MANAGEMENT TOOLS AND ANALYSING INTEGRATION MODELS FOR MOBILITY ENTERPRISE

The mobile market is growing. More and more business units, (BUs) at the multinational company ABB start considering utilizing mobility to create business value, by offering product/system enhancement and by offering new services. However, at present, there is no standard way to realize this and they struggle with the security challenges for their solution. This thesis work will focus on investigating the Mobile Device Management (MDM) market and analyze how the existing technologies address all security requirements of a mobility solution. The main goal is to investigate how multi criteria methods can be applied to facilitate the choice of the most adequate MDM tool. It needs to provide a secure common architecture and integrate with existing backend infrastructures. The benefits include: (1) enabling the employees to use their own mobile devices in a secure way for working with the enterprise, (2) reliably integrating a backend system for new services in enterprise mobility, and (3) providing a (proven) secure solution to control and manage mobility on MDM technology

Langerhans Cell Histiocytosis Followed by Hodgkin Lymphoma: A Case Report

Langerhans cell histiocytosis (LCH) is a rare neoplasm defined as the proliferation of bone marrow langerhans cells, which is a kind of dendritic cells. The major pathological features of LCH are expression of CD1a and S100 as well as Birbeck granules. Its presentation can differ from a mild bone lesion to a multi-systemic evolved malignant neoplasm; however, the latter outcome is almost rare. Thus, LCH is mostly known as a benign neoplasm. In this study, we present a case of LCH followed by Hodgkin lymphoma (HL). Accompaniment of this disease with malignant lymphoma is rare and considered as case report. Several cases in which malignant lymphoma occurred prior to LCH are reported; however, few cases can be found with LCH followed by malignant lymphomas

Protective effects of quercetin on thioacetamide-induced acute liver damage and its related biochemical and pathological alterations

Background Acute liver damage may be followed by biochemical, behavioral, and pathological alterations, which can end up in serious complications and even death. Aim The aim of this study was to determine whether quercetin, a flavonoid compound, which is also known to have cell-protective, antioxidant, and anti-inflammatory effects, has any protective impacts against thioacetamide (TAA)-induced liver damage in rats. Methods Thirty-six Sprague–Dawley rats were divided into three groups: group C1, normal rats; group C2, rats that received a single dose of TAA (350 mg/kg) intraperitoneally; and group E, rats that received a single dose of TAA (350 mg/kg)+300 mg/kg quercetin intraperitoneally. At the end, liver enzymes and plasma ammonia (NH4) were measured, and pathological analysis of the liver carried out. Results The measured serological markers except for total bilirubin (alanine aminotransferase, aspartate aminotransferase, and NH4) showed a significant decrease in group E compared with group C2. The quercetin-treated group showed a significantly lower clinical grade of encephalopathy. Pathological findings showed a significantly lower piecemeal necrosis in group E compared with group C2. Moreover, there was a nonsignificant decrease in focal necrosis, apoptosis, and focal inflammation in group E compared with group C2. Portal inflammation scores were lower in group E than in group C2. Therefore, quercetin significantly affected the grade of liver damage, as group E had lower grades compared with group C2 (P<0.05). Conclusion Overall, quercetin showed positive effects on both the liver injury and its related behavioral and biochemical changes

Prevalence of Persistent Pulmonary Hypertension of the Newborn and Associated Factors in Term Neonates Born in Southeast of Iran, 2020

Background and purpose: Infants with persistent pulmonary hypertension (PPHN) are readmitted to hospital three times more than other infants or die after discharge. The disease imposes a high cost on families and health systems. In this study, for the first time, the prevalence of PPHN and associated factors were investigated in mature neonates born in southeast of Iran. Materials and methods: In this cross-sectional study, the clinical records of 1859 infants born in Kerman Afzalipour Hospital, 2020 were reviewed. Infants hospitalized from delivery, congenital heart disease, other differential diagnoses of PPHN, and evidence of genetic diseases were excluded from the study. Then, mature infants with clinical evidence of PPHN underwent Doppler echocardiography to confirm the final diagnosis. Information about pregnancy, childbirth, infant gender, birth, 1-minute and 5-minute Apgar scores, and advanced respiratory support were also obtained. Data were analyzed by SPSS V25. Results: Out of 229 neonates meeting the inclusion criteria, 31 (11.9%) had PPHN. Signification relationship was observed between frequency of PPHN and cesarean delivery and 5-minute minute Apgar score (P0.05). The mean parameters of PPHN, including tricuspid annular plane systolic excursion (TAPSE), tricuspid regurgitation rate, mean pulmonary artery pressure, and pulmonary artery diameter were significantly higher in infants delivered by cesarean section than those born by normal vaginal delivery group (P<0.05). Conclusion: Further multicenter studies with larger sample size over a longer period of time are suggested in southeast of Iran to elicit clear explanations on the association between PPHN and maternal, fetal, and neonatal factors

The Effectiveness of a Radiation Safety Training Program in Increasing the Radiation Safety Knowledge of Physicians: A Pilot Study

Background Ionizing and non-ionizing radiation are widely used in the diagnosis and treatment of diseases. Considering the potential risks of radiation, radiation safety training courses are important for medical staff. Objective The aim of this study was to investigate the effectiveness of one-day radiation safety training program in increasing the radiation safety knowledge of physicians. Methods In this descriptive-analytical study, subjects were 12 physicians (6 general practitioners and 6 nonradiologist specialists) participated in the training program organized by Qazvin University of Medical Sciences in 2018. A researcher-made questionnaire was used for surveying physicians before and after the training. The mean and standard deviation of the scores were first calculated. Then, the pre- and post-test scores were compared using Wilcoxon signed-rank test, and the correlation of these scores with their age, gender, expertise area, and work experience was examined by Spearman's correlation test. Findings The mean total scores of the physicians before and after training were 7.00±2.56 (ranged 3-11) and 11.92± 2.31 (ranged 8-15) out of 18, respectively. The radiation safety knowledge of physicians significantly increased after training (P<0.001). No significant relationship was found between their scores and their age, gender, expertise area and work experience. Conclusion The radiation safety training program was effective in increasing the radiation safety knowledge of physicians and it can be used for a larger community of physicians

Isolation and characterization of anti c-met single chain fragment variable (scFv) antibodies

The receptor tyrosine kinase (RTK) Met is the cell surface receptor for hepatocyte growth factor (HGF) involved in invasive growth programs during embryogenesis and tumorgenesis. There is compelling evidence suggesting important roles for c-Met in colorectal cancer proliferation, migration, invasion, angiogenesis, and survival. Hence, a molecular inhibitor of an extracellular domain of c-Met receptor that blocks c-Met-cell surface interactions could be of great thera-peutic importance. In an attempt to develop molecular inhibitors of c-Met, single chain variable fragment (scFv) phage display libraries Tomlinson I + J against a specific synthetic oligopeptide from the extracellular domain of c-Met receptor were screened; selected scFv were then characterized using various immune techniques. Three c-Met specific scFv (ES1, ES2, and ES3) were selected following five rounds of panning procedures. The scFv showed specific binding to c-Met receptor, and significantly inhibited proliferation responses of a human colorectal carcinoma cell line (HCT-116). Moreover, anti- apoptotic effects of selected scFv antibodies on the HCT-116 cell line were also evaluated using Annexin V/PI assays. The results demonstrated rates of apoptotic cell death of 46.0, 25.5, and 37.8% among these cells were induced by use of ES1, ES2, and ES3, respectively. The results demonstrated ability to successfully isolate/char-acterize specific c-Met scFv that could ultimately have a great therapeutic potential in immuno-therapies against (colorectal) cancers